Organ Of Corti's Negative Intracellular Polarization

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Report Number: WADD TR 60-778
Author(s): Rice, Edward A.
Corporate Author(s): Biomedical Laboratory, Aerospace Medical Laboratory
Laboratory: Biomedical Laboratory, Aerospace Medical Laboratory
Date of Publication: 1961-01
Pages: 10
Contract: Laboratory Research - No Contract
DoD Project: 7232
DoD Task: 71789
Identifier: AD0255256

The negative potential located between the basilar membrane and the reticular lamina of the guinea pigs was investigated busing several types of electrodes from 3 to 24 microns in diameter, This potential was found intracellular in origin and located within the organ of Corti. They hypothesis that the negative potential found in the scala media of hypoxic animals represents a "leakage" of the organ of Corti's negative intracellular polarization is supported by these experiments. The negative intracellular polarization of the organ of Corti was found to exist during the life span of the microphonics. The significance of these findings in explaining the origin of microphonics is discussed.

Provenance: IIT

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