Endocrine and Metabolic Response of Dogs to Whole-body Vibration

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Report Number: AMRL-TDR-64-54
Author(s): Blivaiss, Ben B., Litta-Modignani, Renatto, Galansino, Giorgio, Foa, Piero P.
Corporate Author(s): Chicago Medical School
Laboratory: Biophysics Laboratory
Date of Publication: 1964-06
Pages: 19
Contract: AF 33(616)-6889
DoD Project: 7231
DoD Task: 723101
Identifier: AD0606054

Abstract:
To determine the endocrine and metabolic response of restrained dogs to whole-body vibration, pentobarbital anesthetized and non-anesthetized dogs were vibrated along the z axis while restrained in dorsal recumbency. After vibration of anesthetized dogs at either 4 cps, 0.4 g for 30 minutes or 2 hours, or at 10 cps, 2.3 g for 2 hours, there was an average increase of 4.08 mcg 17 hydroxycorticosteroids (17-OH-CS) per 100 ml plasma and a significant increase in blood epinephrine but not serotonin or norepinephrine. Shaking at 4 cps, 1.7 g for 30 minutes produced less of a change in plasma 17-OHCS than at 0.4 g. However, shaking at 4 cps for 6 hours led to greater increase in plasma 17-OH-CS at 1.7 g than 0.4 g. Non-anesthetized dogs shaken at 4 cps for 30 minutes had a greater increase of plasma 17-OH-CS than similarly shaken anesthetized dogs. Possible mechanisms for alterations in endocrine function are discussed.

Provenance: RAF Centre of Aviation Medicine

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