The Pathology And Mechanics Of Experimental Cerebral Concussion
Report Number: WADD TR 61-256
Author(s): Friede, Reinhard L.
Corporate Author(s): Biomedical Laboratory; Aerospace Medical Laboratory
Laboratory: Biomedical Laboratory; Aerospace Medical Laboratory
Date of Publication: 1961-03
Pages: 23
Contract: Laboratory Research - No Contract
DoD Project: 7231
DoD Task: 71786
Identifier: AD0266210
Abstract:
A blow to the cat's head produces an abrupt displacement at the craniocervical junction. This results in a fiber lesion at the ventral circumference of the spinal cord at C-1, opposite the prominence of the odontoid process. Thick fibers are affected more severely than thin fibers. Axonal reaction is found in the nucleus gigantocellularis of the reticular formation, the nucleus vestibularis lateralis, the red nucleus, and others.All these nuclei send their descending fibers through the damaged region. Changes are consistent. Intensity is related to the severity of concussion so that the duration of concussion can be estimated histologically without knowledge of the experimental data. The mechanical forces used to produce concussion are the same type described by other investigators. An experimental analysis of the mechanical factors involved in the production of damage reveals stretch and flexion to be most important.
Provenance: IIT
Author(s): Friede, Reinhard L.
Corporate Author(s): Biomedical Laboratory; Aerospace Medical Laboratory
Laboratory: Biomedical Laboratory; Aerospace Medical Laboratory
Date of Publication: 1961-03
Pages: 23
Contract: Laboratory Research - No Contract
DoD Project: 7231
DoD Task: 71786
Identifier: AD0266210
Abstract:
A blow to the cat's head produces an abrupt displacement at the craniocervical junction. This results in a fiber lesion at the ventral circumference of the spinal cord at C-1, opposite the prominence of the odontoid process. Thick fibers are affected more severely than thin fibers. Axonal reaction is found in the nucleus gigantocellularis of the reticular formation, the nucleus vestibularis lateralis, the red nucleus, and others.All these nuclei send their descending fibers through the damaged region. Changes are consistent. Intensity is related to the severity of concussion so that the duration of concussion can be estimated histologically without knowledge of the experimental data. The mechanical forces used to produce concussion are the same type described by other investigators. An experimental analysis of the mechanical factors involved in the production of damage reveals stretch and flexion to be most important.
Provenance: IIT